Importance of cannabis in endocannabinoid system

Cannabis and the endogenous cannabinoid system are closely related. If you want to understand the effects of cannabis from a physiological point of view, it is important to understand what the internal cannabis system is. The discovery of this network of biochemical messengers represented a major advance in cannabis medicine and science. Below is a brief description of how the endocannabinoid system works and the history of its discovery.

 

What is the internal hemp system?

 

The endocannabinoid system (ECS) is widely talked about in the media today because of its association with cannabis. Our bodies produce endogenous cannabinoids, and the most studied are anandamide and 2-AG. Endogenous cannabinoids interact with cannabinoid receptors. When these receptors are "unlocked" by endogenous cannabinoids, they send chemical messages to the body to perform specific tasks such as regulating the immune system.

 

There is also another cannabinoid receptor called GPR55, which has not been fully studied compared to CB1 and CB2. Metabolic enzymes play a role in the reabsorption of endocannabinoids when they are not needed.

 

 

 

It is helpful to understand how endocannabinoids type 1 (called CB1) and type 2 (CB2) activate cannabinoid receptors. The former is found in the brain, central nervous system and some peripheral tissues, and the latter is found primarily in cells of the immune system.

 

Receptors are proteins that generally bind to specific factors (called ligands), which in turn cause malformations that lead to cellular or biological reactions. The two species identified so far (CB1 and CB2) constitute the endogenous cannabinoid system. Medicinal australia considers cannabinoids to be "messengers" that affect our bodies, and cannabinoid receptors are receptors for these messages. 

 

An increasing number of preclinical and clinical trials of compounds that regulate the endogenous cannabinoid system may lead to new therapeutic approaches in many conditions where current treatment does not fully meet patients' needs. 

 

Cannabis and the internal hemp system

 

Hemp plants produce THC, CBD, CBN, THCA and about 90 other plants from the cannabis plant ("plant" means "plant"). These cannabinoids act on cannabinoid receptors because they mimic the structure of the endogenous cannabinoids that our bodies produce. Therefore, many functions involving the endogenous cannabinoid system are affected by cannabis use. Not all cannabinoids work the same way. For example, THC has psychoactive effects, but CBD does not.

 

Functions of the internal hemp system

 

The endogenous cannabinoid system helps regulate sleep, mood, reproduction, motor control, body temperature, immune system, pain, memory and other physiological processes. ECS is usually presented in the media as a "regulatory system" that corrects irregularities when the balance is unbalanced. Many patients use cannabis to help regulate these functions from medicinal herbs.

 

Why do people react differently to cannabis?

 

While consuming any form of cannabis, one is also ingesting cannabinoids. This logically leads to changes in body function. But from a biological point of view, we are not all the same, and the number of sensors located in different body parts varies. This unique combination continues to excite our reaction to cannabis for more or less controlled reasons.

 

Conclusion: it was discovered about 25 years ago, but there is still a long way to understand the potential of cannabis in ECS fully.

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